Grabbers Abstract Compact RNA structural motifs control many aspects of gene expression, but we lack methods for finding these structures in the vast expanse of multi-kilobase RNAs.To adopt specific 3-D shapes, many RNA modules must compress their RNA backbones together, bringing negatively charged phosphates into close proximity.This is often acco
Summary: Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with unclear mechanisms.Here, we investigated Eye Spray the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic nucleus (PIL) in hippocampal seizures.Using c-fos mapping and calcium fiber photometry, we found that PIL CR neurons
Designing targeted-delivering and stimuli-responsive nanocarriers for photodynamic therapy (PDT) is an appealing method, especially, targeting delivery of photosensitizers to mitochondria as the most sensitive cellular organelles to reactive oxygen species (ROS) could significantly enhance the Wall Decor therapeutic efficacy of PDT.In this study, w
The purpose of the research is to show the political impression management of the president and vice president candidates, Prabowo Subianto and Sandiaga Uno in social media, in the presidential election 2019.Instagram is the focus of social media in the research.Specifically, the research would like to know the created impression in each Instagram